Keywords: Biomarkers, Cancer
Motivation: The role of parameters derived from novel non-Gaussian diffusion models in identifying prognostic factors associated with nasopharyngeal cancer has not been reported.
Goal(s): To explore the association between diffusion parameters and prognostic factors in NPC, including Ki-67, EGFR, and tumor-stroma ratio.
Approach: Eighty-three NPC patients performed continuous-time random-walk (CTRW) and fractional order calculus (FROC) models. ROC analysis was conducted using the diffusion parameters to evaluate accuracy in identifying prognostic factors.
Results: Diffusion parameters from CTRW and FROC models can distinguish EGFR and TSR expression, but not Ki-67.
Impact: Non-Gaussian diffusion parameters can non-invasively assess prognostic factors in NPC and help doctors better manage NPC patients.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords