Abstract #1967

In vivo T1-mapping using Open-MOLLI in GE scanners

Andreia S Gaspar¹, Paul JC Hughes², Jon-Fredrik Nielsen³, Neil J Stewart², James M Wild², Teresa M Correia^4,5, and Rita G Nunes¹

¹Instituto de Sistemas e Robótica–Lisboa and Departamento de Bioengenharia, Instituto Superior Técnico, Universidade de Lisboa, Lisbon, Portugal, ²POLARIS, Division of Clinical Medicine, School of Medicine & Population Health, University of Sheffield, Sheffield, United Kingdom, ³Functional MRI Laboratory, Department of Radiology, University of Michigan, Functional MRI Laboratory, Department of Radiology, MI, United States, ⁴Centre of Marine Sciences UAlg, Universidade do Algarve, Faro, Portugal, ⁵School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom

Synopsis

Keywords: Quantitative Imaging, Relaxometry, Open-Source; T1 mapping; Myocardial; MOLLI

Motivation: The open-source myocardial T1 mapping (Open-MOLLI) sequence allows the application of the same methodology in different settings for improved reproducibility.

Goal(s): We aim to test Open-MOLLI, originally developed on a Siemens system, on a GE scanner.

Approach: The Open-MOLLI sequence was adapted to a 3T GE vendor system, and was acquired in 2 subjects. T1 of one axial slice of the brain was estimated, and white matter (WM) and grey matter (GM) T1 values were compared with the literature.

Results: Open-MOLLI was successfully adapted to the GE system, allowing to estimate T1-values that are consistent with literature values for GM and WM.

Impact: The open-source myocardial T1 mapping (Open-MOLLI) was successfully adapted and tested on a GE Signa 3T PET-MR scanner. The sequence is now ready to be applied in inter-scanner reproducibility brain studies. Triggering will be added next for cardiac applications.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.