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Abstract #1971

Multi-site use of a vendor-agnostic, open-source protocol (VOP) framework to validate and share open-source pulse sequences

Sairam Geethanath1, Anais Artiges2, Tobias Block2, Qingping Chen3, Tiago F. Fernandes 4, Sandeep Ganji5, William A. Grissom 6, Daniel Hoinkiss 7, John Thomas Vaughan Jr.8, Amaresha Shridhar Konar8, Simon Konstandin7, Vasco Mascarenhas 9, Martijn Nagtegaal 10, Jon Fredrik Nielsen11, Rita G Nunes4, Mojtaba Shafiekhani 3, and Maxim Zaitsev 3
1Johns Hopkins University, Ellicott City, MD, United States, 2New York University, New York, NY, United States, 3Division of Medical Physics, Department of Diagnostic and Interventional Radiology, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany, Freiburg, Germany, 4Universidade de Lisboa, Lisbon, Portugal, Lisbon, Portugal, 5Philips Healthcare, Rochester, Minnesota, USA, Baltimore, MD, United States, 6Department of Biomedical Engineering, Case School of Engineering, Case Western Reserve University, Cleveland, OH, United States, Cleveland, OH, United States, 7Fraunhofer Institute for Digital Medicine MEVIS, Bremen, Germany, Bremen, Germany, 8Columbia University in the City of New York, New York, NY, United States, 9Hospital da Luz Learning Health, Luz Saúde, Lisboa, Portugal, Lisbon, Portugal, 10C.J. Gorter MRI Center, Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands, Leiden, Netherlands, 11University of Michigan Ann Arbor, Ann Arbor, MI, United States

Synopsis

Keywords: Software Tools, Software Tools

Motivation: A community-driven vendor-agnostic, open-source protocols (VOP) framework will expand the acquisition of reproducible MR data by collaboratively, safely, effectively, and ethically sharing magnetic resonance (MR) protocols.

Goal(s): To validate and share two Pypulseq and GammaStar generated pulse sequences at multiple sites and two field strengths

Approach: We acquired T1w, T2w, and quantitative relaxometric data from six sites on the Siemens, Philips, and the mri4all Zeugmatron1 platforms; sharing the code, data, images and documentation; compliant with the framework requisites

Results: The sites fulfilled the requirements of the framework, and sites performing qMR provided similar and accurate T1 and T2 measures on the respective phantoms

Impact: We demonstrated the expanded use of the VOP framework to validate and share the IRSE and TSE sequences across sites, vendors, software versions, and two field strengths. This framework created an online platform to interact and share pulse sequences.

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Keywords