Abstract #1994

Improved Breast Cancer Characterization with High-Resolution 3D T2WI-SPACE at Equivalent Scan Times to Conventional 2D FSE-T2WI

Kazushige Ichikawa¹, Hiroko Satake², Mami Iima³, Satoko Ishigaki², Yutaka Kato¹, and Shinji Naganawa²

¹Department of Radiological Technology, Nagoya University Hospital, Nagoya, Japan, ²Department of Radiology, Nagoya University Graduate School of Medicine, Nagoya, Japan, ³The Department of Fundamental Development for Advanced Low Invasive Diagnostic Imaging, Nagoya University Graduate School of Medicine, Nagoya, Japan

Synopsis

Keywords: Breast, Breast

Motivation: There are no reports comparing 3D T2WI optimized through phantom studies with 2D T2WI for breast MRI.

Goal(s): To optimize 3D T2WI in a phantom study and compare the image quality of the optimized 3D T2WI with 2D T2WI in clinical breast MRI.

Approach: A Phantom was scanned for the optimization of 3D T2WI as for contrast ratio and resolution. This IRB-approved retrospective study demonstrated the quantitative and qualitative analysis between optimized 3D T2WI and 2D T2WI.

Results: The optimized 3D T2WI with variable refocusing flip angle demonstrated excellent conspicuity with higher resolution compared to 2D T2WI, while maintaining the same scanning time.

Impact: Our findings strongly support the feasibility of high-resolution 3D T2WI for implementation in clinical settings, offering valuable information to contrast-enhanced MRI for breast cancer characterization. This technique would show promise for improving lesion differentiation, prognosis prediction, and treatment efficacy assessment.

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