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Abstract #2034

Diagnostic Value of Combined IVIM, DKI, and DCE-MRI in Differentiating Benign and Malignant Breast Lesions

Yongmiao Wang1, Jun Li1, Nan Zhou1, Yanxin Zhou1, Fanxin Fu1, Chao Gao1, and Meining Chen2
1The First Affiliated Hospital of Kunming Medical University, Kunming, China, 2MR Research Collabrotion,Siemens Healthineers Ltd., Chengdu, China

Synopsis

Keywords: IVIM, IVIM, Perfusion,DKI,diffusion acquisition,breast

Motivation: Non-invasive imaging like IVIM, DKI, and DCE-MRI improves diagnostic accuracy by revealing tissue characteristics and aiding differentiation of benign and malignant breast lesions.

Goal(s): This study assesses the diagnostic value of a combined IVIM, DKI, and DCE-MRI approach for distinguishing breast lesion types, compared to single-method models.

Approach: Data from 33 confirmed breast lesions were analyzed retrospectively. MRI parameters (Ktrans, Kep, Ve, MK, MD, D) were compared across lesion types using ROC analysis.

Results: Malignant lesions had significantly higher Ktrans, Kep, and MK values and lower D and MD values, with the combined model demonstrating superior diagnostic efficacy.

Impact: The integration of IVIM, DKI, and DCE-MRI enhances diagnostic precision in breast lesion differentiation, potentially improving clinical decision-making and patient management by providing a more accurate non-invasive assessment, which could guide tailored treatment strategies for breast cancer patients.

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Keywords