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Abstract #2110

Initial Experience of Cardiac Multi-parametric Mapping at 5.0T with Single-shot Cartesian Acquisition and Dictionary Matching

Zhenfeng Lyu1, Hongzhang Huang1, Huili Yang2, Peng Hu1, and Haikun Qi1
1School of Biomedical Engineering & State Key Laboratory of Advanced Medical Materials and Devices, ShanghaiTech University, Shanghai, China, Shanghai, China, 2United Imaging Healthcare, Inc., Shanghai, China, Shanghai, China

Synopsis

Keywords: Myocardium, Quantitative Imaging, Ultra-high field; Dictionary matching; T1; T2; 5.0T; Cartesian;

Motivation: While 5.0T ultra-high field MRI offers superior resolution and signal-to-noise ratio, it introduces pronounced field inhomogeneity effects, which hinders myocardial quantification approaches.

Goal(s): To validate the feasibility of simultaneous myocardial multi-parametric mapping (MultiMap) on a 5.0T MRI scanner.

Approach: Cardiac MultiMap was implemented at 5.0T using single-shot Cartesian acquisition and dictionary-based quantification with pixel-wise B1+ correction, replacing bSSFP with FLASH readout to improve robustness to B0 field inhomogeneity. Quantification accuracy was evaluated through phantom and in-vivo experiments.

Results: T1 and T2 can be accurately estimated using MultiMap at 5.0T.

Impact: The validation of simultaneous myocardial multi-parametric mapping at 5.0T demonstrated promising performance, with potential for more accurate myocardial assessments in clinical settings.

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Keywords