Meeting Banner
Abstract #2118

Nomogram Based on Breast MRI for Predicting Treatment Decisions in HR-Positive Breast Cancer

meihong Sheng1 and lihua zhang2
1Radiology, the Affiliated 2 Hospital of Nantong University, Nantong, China, 2Xiamen Branch of Zhongshan Hospital Affiliated to Fudan University, Xiamen, China

Synopsis

Keywords: Breast, Breast, HR-Positive Breast Cancer,Nomogram ; Treatment Decisions

Motivation: Accurate recurrence risk stratification is crucial in HR+ breast cancer for guiding treatment. Multi-gene tests can be costly and have limitations, highlighting the need for a cost-effective, reliable alternative like MRI-based nomograms.

Goal(s): To evaluate the effectiveness of MRI-based nomogram in predicting CTS5 for adjuvant therapy decisions in HR+ breast cancer.

Approach: The study analyzed follow-up data of 106 patients and divided 303 patients into Training and validation cohorts. A nomogram was assessed using AUC and calibration metrics for CTS5 risk stratification.

Results: The nomogram demonstrated high discrimination and calibration in CTS5 classification, aligning with actual recurrence outcomes and supporting precision treatment planning.

Impact: This MRI-based nomogram enables personalized treatment for HR-positive breast cancer , thus offering a non-invasive, cost-effective approach for recurrence risk stratification and extended endocrine therapy decisions.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords