Keywords: Diffusion Acquisition, New Signal Preparation Schemes, Diffusion pore imaging
Motivation: MRI diffusion pore imaging (DPI) is a potentially powerful tool for non-invasive pathological examinations. Average pore sizes and shapes can be reconstructed using modified diffusion measurements.
Goal(s): As pore imaging relies on averaging over pores in regions of interest to go beyond the resolution of classical MR imaging, in-vivo applications require the combination of DPI with conventional MR imaging to estimate the pore sizes in those regions.
Approach: A conventional spin-echo imaging sequence was combined with a pore imaging sequence to measure a phantom containing capillaries.
Results: We successfully reconstructed different pore sizes at different locations from a single DPI measurement.
Impact: Localized diffusion pore imaging allows reconstructing several pore sizes in different regions from a single sample. This was achieved using a diffusion pore imaging sequence with imaging readout and a phantom containing capillaries of two different sizes.
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