Meeting Banner
Abstract #2189

Real-time MR Thermometry to Monitor Microwave Ablation: Validation in Oncopigs using Immediate Post-Ablation MRI and Gross Pathology

Qing Dai1,2, Jason Chiang1, Glen Nyborg1, Shu-Fu Shih1, David S. K. Lu1, and Holden H. Wu1,2
1Radiological Sciences, University of California, Los Angeles, Los Angeles, CA, United States, 2Bioengineering, University of California, Los Angeles, Los Angeles, CA, United States

Synopsis

Keywords: MR-Guided Interventions, Preclinical, Liver, microwave ablation, Oncopig, clinical workflow

Motivation: MR thermometry can monitor microwave ablation (MWA) and predict ablation zones, but it's prone to image quality degradation during MWA and lacks validation for predicted ablation zone dimensions.

Goal(s): 1) Develop a real-time MR thermometry technique for monitoring MWA; 2) validate the MR thermometry-predicted ablation zone with immediate post-ablation MRI and gross pathology in a preclinical model.

Approach: MRI-guided MWA with a respiratory-triggered MR thermometry sequence was performed in two Oncopigs with induced liver tumors.

Results: MR thermometry can monitor MWA without noticeable artifacts. Thermometry-predicted ablation zones were in general agreement with post-ablation MRI and gross pathology.

Impact: The experimental setup using the Oncopig cancer model demonstrates a promising preclinical framework for developing, validating, and refining MR thermometry techniques to improve MRI-guided MWA for better outcomes.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords