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Abstract #2192

Temperature Mapping During MR-Guided Cryoablation Using a FLORET UTE Sequence

Moritz Gutt1,2, Othmar Belker1,2, Julienne Scheller1, Simon Schröer1,2, Frank Wacker1,2, Bennet Hensen1,2, and Marcel Gutberlet1,2
1Department of Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany, 2Research Campus STIMULATE, Magdeburg, Germany

Synopsis

Keywords: Thermometry/Thermotherapy, Thermometry

Motivation: Frozen tissue has a rapid T2* decay and low net magnetization. It thus appears as a signal void in most MR images. As tissue necrosis only happens between -20 and -40 °C it is not possible to distinguish between frozen and necrotic tissue during MR-guided cryoablation.

Goal(s): Our goal was to estimate temperatures in frozen tissue.

Approach: To encounter the rapid T2* decay we implemented an ultrashort echo-time sequence with a FLORET readout and estimated the temperature from the signal intensity.

Results: Our method provided a good temperature accuracy combined with a high temporal resolution.

Impact: During MR-guided cryoablation of tumors the proposed method could be used for therapy monitoring. It could thus enable a safer and more targeted way of destroying the tumor but not too much of the surrounding healthy tissue.

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Keywords