Keywords: Thermometry/Thermotherapy, Thermometry/Thermotherapy
Motivation: Accurate MR thermometry methods are critical to the successful delivery of hyperthermia thermal therapy treatments.
Goal(s): Evaluate a k-space based B0 correction technique for MR thermometry in MR guided focused ultrasound hyperthermia treatments.
Approach: The performance of a previously developed thermal controller was evaluated using 3D PRF MR thermometry both with and without k-space field drift correction in phantom and in vivo rabbit undergoing MRgFUS hyperthermia treatment. The MRTI precision was also evaluated in a single human subject under non-heating conditions.
Results: Drift corrected MRTI improved targeting accuracy of a PID controlled hyperthermia treatment in both phantoms and rabbits.
Impact: Accurate MR thermometry is critical to the successful delivery of hyperthermia treatments, where a fraction of degree accuracy can impact treatment outcome. Implementing a k-space based B0 correction technique achieves substantially improved accuracy in MR guided focused ultrasound hyperthermia treatments.
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