Abstract #2209

Validation of Multi-modality Image Registration for Glioblastoma Treatments on the MR-Linac

Tom Gribilas¹, Liam S.P. Lawrence², Angus Z Lau², Ryan Oglesby³, James Stewart⁴, Greg Stanisz², and Brige Paul Chugh⁵

¹Mathematics and Statistics, McMaster University, Hamilton, ON, Canada, ²Medical Biophysics, University of Toronto, Toronto, ON, Canada, ³Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins Medicine, Baltimore, MD, United States, ⁴Radiation Oncology, , Sunnybrook Health Sciences Centre, Toronto, ON, Canada, ⁵Sunnybrook Health Sciences Centre, Toronto, ON, Canada

Synopsis

Keywords: MR-Guided Radiotherapy, Radiotherapy, Multi-modality Image Registration, MR-Linac

Motivation: Improve consistency, efficiency and accuracy of verifying image registrations, which are a potential major failure mode in MR-Linac treatments.

Goal(s): Develop a quantitative method for automatically verifying image co-registration.

Approach: Brain MR and CT image registrations were assessed using five different similarity metrics. Validation of registration involved comparing the vendor-provided registration algorithm with an independent algorithm to identify the most useful image similarity metrics.

Results: A process for automated registration analysis was developed. SSIM and MSE were the most promising metrics for measuring registration accuracy.

Impact: A new tool was developed for verifying the accuracy of registration of MR images, which could be used to automatically detect inaccurate registrations during the treatment workflow on the MR-Linac.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.