Keywords: Muscle, Quantitative Imaging, Statistical Shape Modeling (SSM), Muscle Strength, Aging, and Sarcopenia
Motivation: Decline in muscle mass does not explain decline in muscle strength related to aging providing a compelling gap to investigate contribution of shape features in muscle strength.
Goal(s): Our goal was to use statistical shape modeling (SSM) to investigate shape features of quadriceps muscles associated with muscle strength.
Approach: We used SSM to extract dominant shape features of quadriceps. Extracted shape features were used to predict muscle strength.
Results: Muscle shape features increased muscle strength prediction compared to muscle volume alone. These shape features may reflect architecture rearrangement of the quadriceps as a result of aging.
Impact: Shape features of quadriceps muscles extracted from statistical shape modeling demonstrated a higher prediction of muscle strength of the rectus femoris, the vastus lateralis and the vastus medialis muscles in healthy subjects.
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