Abstract #2279

Assessing the Feasibility of PROPELLER DWI for Prostate Imaging in Patients with Metal Implants

Yu-Ching Chen^1,2, Cheng-Ya Yeh², Yi-Chen Chen², Chia-Wei Lee³, Charng-Chyi Shieh³, Chien-Yuan Lin³, Kao-Lang Liu¹, and Yeun-Chung Chang²

¹Department of Medical Imaging, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan, ²Department of Medical Imaging, National Taiwan University Cancer Center and National Taiwan University College of Medicine, Taipei, Taiwan, ³GE Healthcare, Taipei, Taiwan

Synopsis

Keywords: Pelvis, Prostate, PROPELLER-DWI

Motivation: Propeller-DWI could reduce significant image distortion from metal implants.

Goal(s): This study aims to investigate the improvement of image quality and the feasibility of ADC values in PROPELLER DWI for prostate with metal implants.

Approach: We collected DWI images from 88 male participants. Our results showed the reduced distortion in the PROPELLER-DWI images, along with a strong liner correlation of ADC values between two DWI methods.

Results: Based on the lesion detection rate of mean ADC values, the optimal cut-off ADC value for PROPELLER-DWI in tumor and lesion diagnosis should be set higher (1400x10^-6mm²/s) than the cut-off ADC value for clinical EPI-DWI (930x10^-6mm²/s).

Impact: This study indicates reduced distortion of tissues near metal implants in PROPELLER-DWI and a strong linear correlation of ADC values between PROPELLER-DWI and EPI-DWI, suggesting PROPELLER-DWI would be valuable for the diagnosis of prostate cancer in patients with metal implants.

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