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Abstract #2300

CEST fluid artifact identification by steady-state signal fitting (FISS)

Xingwang Yong1, Longjie Zhou1, Chi Zhang2, Yi-Cheng Hsu3, Chunqiu Su2, Shanshan Lu2, and Yi Zhang1
1Zhejiang University, Hangzhou, China, 2The First Affiliated Hospital of Nanjing Medical University, Nanjing, China, 3MR Collaboration, Siemens Healthcare Ltd., Shanghai, China

Synopsis

Keywords: CEST / APT / NOE, CEST & MT, fluid suppression

Motivation: The fluid compartment may show as hyperintense or hypointense artifacts on post-processed CEST images.

Goal(s): To propose a method identifying the fluid compartment on CEST images for improved image reading and quantitative analysis.

Approach: The z-spectrum between -1 and 1 ppm is fitted to a steady-state signal model. The B1, fitted parameters, and fitting residue are used as features to differentiate fluid and tissue compartments.

Results: The proposed method shows excellent performance for identifying fluid, with an AUC of 1. The post-processed CEST image masked by the fluid mask has improved readability.

Impact: The proposed method shows the ability to identify the fluid compartments on CEST images,which can help mitigate fluid artifacts in quantitative analysis and improve image reading.

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Keywords