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Abstract #2310

Direct Revascularization Reduces Arterial Transit Time in Moyamoya Patients

Moss Y Zhao1, Michael Moseley2, and Gary K Steinberg1
1Department of Neurosurgery, Stanford University, Stanford, CA, United States, 2Department of Radiology, Stanford University, Stanford, CA, United States

Synopsis

Keywords: Arterial Spin Labelling, Stroke

Motivation: Moyamoya affects hemodynamics and a hallmark is delayed transit time. However, the non-invasive assessments of transit time in Moyamoya remains an open question.

Goal(s): Measure transit time before and after revascularization using multi-delay ASL and DSC MRI.

Approach: Transit time in 52 Moyamoya patients was measured using ASL and DSC before and after revascularization. Results between these two modalities were compared in regions affected by vasculopathy.

Results: Transit time decreased significantly after revascularization. ASL and DSC results were significantly and positively correlated.

Impact: ASL can be utilized to evaluate transit time in Moyamoya patients before and after direct revascularization.

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