Keywords: fMRI Acquisition, Acquisition Methods, rFOV Imaging
Motivation: Reduced field-of-view (rFOV) imaging can improve spatio-temporal resolution in functional MRI (fMRI), but its impact on activation detection has not (to our knowledge) been examined.
Goal(s): To design a short (6ms) outer-volume-suppression (OVS) RF pulse for rFOV fMRI, and investigate its impact on the sensitivity and reliability of BOLD fMRI activation.
Approach: We obtained accelerated (R=7.5) BOLD data during four repetitions of a block finger-tapping task, with and without OVS. We assessed test-retest reliability of the activation maps using receiver-operating-characteristic (ROC) analysis.
Results: The 6 ms OVS pulse somewhat lowers sensitivity to motor cortex BOLD activation, but somewhat improves test-retest reliability.
Impact: Outer-volume suppressed fMRI can produce reliable activation maps, and may be a promising candidate for high-resolution (e.g., layer-specific) fMRI.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords