Abstract #2361

Risk Factors for Co-existing Extracranial Carotid and Intracranial Artery High-Risk Atherosclerotic Plaques: A MR Imaging Study

Xiaoyi Chen¹, Dandan Yang², Xiaowei Song³, Shuo Chen⁴, Huiyu Qiao⁴, Chun Yuan⁵, Zhuozhao Zheng¹, and Xihai Zhao⁴

¹Department of Radiology, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China, ²Department of Radiology, Beijing Geriatric Hospital, Beijing, China, ³Department of Neurology, Beijing Tsinghua Changgung Hospita, School of Clinical Medicine, Tsinghua University, Beijing, China, ⁴Center for Biomedical Imaging Research, Department of Biomedical Engineering, Tsinghua University School of Medicine, Beijing, China, ⁵Department of Radiology, University of Washington, Seattle, WA, United States

Synopsis

Keywords: Stroke, Blood vessels, risk factors; high-risk plaque

Motivation: Atherosclerosis is a systematic disease that usually affects multiple vascular beds. High-risk atherosclerotic plaques (HRPs) more likely lead to ischemic events. Determination of risk factors for co-existing HRPs is important for clinical management.

Goal(s): Our goal was to determine the risk factors for co-existing extracranial carotid and intracranial artery HRPs using MR vessel wall imaging (VWI).

Approach: All patients underwent carotid and intracranial artery MR-VWI to identify HRPs. The associations between risk factors and co-existing extracranial carotid and intracranial artery HRPs were analyzed.

Results: We found that diabetes and family history of cardiovascular disease are independent risk factors for co-existing HRPs.

Impact: To identify the risk factors for co-existing extracranial carotid and intracranial artery HRPs is valuable for precision management and prevention of future adverse events.

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