Keywords: Stroke, Stroke
Motivation: Despite the prevalent use of DTI and DKI in assessing ischemic stroke, these methods fall short in accurately characterizing non-Gaussian diffusion behavior in brain tissues, often leading to an underestimation of microstructural changes.
Goal(s): evaluate the feasibility of the models WMTI and MAPL for the quantitative detection of microstructural changes in brain tissue during ischemic stroke
Approach: This study introduced the model WMTI and MAPL to enhance the assessment of white matter microstructural damage in non-basal ganglia subcortical ischemic stroke
Results: The study proved that the diffusion models WMTI and MAPL are feasible for assessing ischemic stroke.
Impact: Compared to traditional diffusion models DTI and DKI, the novel diffusion model MAPL exhibits higher sensitivity in describing changes in brain tissue microstructure. Additionally, changes observed during follow-up are positively correlated with NIHSS changes, making it a potential biomarker for estimating brain injury in ischemic stroke.
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