Meeting Banner
Abstract #2399

Application of APT and MRS in the Grading of Brain Gliomas

Liqin Liu1, Shenghong Wan1, Kai Ai2, YI Zhu2, and Xin Liao1
1Dpartment of Radiology, Affiliated Hospital of GuiZhou Medical University, Guiyang, China, 2Department of Clinical and Technical Support, Philips Healthcare, Xi'an, China

Synopsis

Keywords: Tumors (Pre-Treatment), Brain, Tumor, MRS, APT

Motivation: Brain glioma is the most common malignant tumor of the central nervous system, with high recurrence and mortality. Treatment and prognosis are related to tumor grade, but conventional MRI has limited specificity. Non-invasive MRI techniques for grading are essential.

Goal(s): To evaluate the application of APT imaging and MRS in preoperative glioma grading.

Approach: A prospective study to assess APT and MRS in differentiating high-grade from low-grade gliomas.

Results: HGG showed higher relative mean APT, Cho/Cr, and Cho/NAA values than LGG. The study showed that the solid components of HGG exhibited higher relative mean APT, Cho/Cr, and Cho/NAA values compared to LGG.

Impact: APT and MRS can predict glioma grade preoperatively. This study suggests that APT and MRS can be used to predict glioma grade preoperatively, providing clinicians with important information for planning treatment strategies and assessing prognosis.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords