Keywords: CEST / APT / NOE, CEST / APT / NOE, Preclinical imaging; Pulse sequence; Image reconstruction; MR fingerprinting
Motivation: High-resolution molecular imaging with chemical exchange saturation transfer (CEST) and magnetic resonance fingerprinting (MRF) is difficult to implement and analyze, even for preclinical studies. Making preclinical CEST-MRF easier would spur rapid development.
Goal(s): We aimed to develop a Bruker ParaVision 360 method and corresponding processing pipeline to easily design a CEST-MRF experiment and quickly evaluate the results.
Approach: The sequence includes a .txt read-in feature for CEST-MRF parameter specification. The MATLAB processing pipeline features a graphical user interface for easy image processing and statistics.
Results: The imaging method and processing pipeline are available on GitHub and make CEST-MRF imaging easy to implement.
Impact: The Bruker ParaVision 360 imaging method and processing pipeline we developed is publicly available and will facilitate CEST-MRF imaging development by making experiments easy to customize and analyze, spurring more rapid CEST-MRF development towards clinical imaging.
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