Meeting Banner
Abstract #2487

Dynamic Functional Connectivity and Coupling Analysis of Triple Networks and White Matter Functional Networks in First-Episode Schizophrenia

Xusha Wu1, Yibin Xi1, and Hong Yin1
1Xi'an People's Hospital (Xi'an Fourth Hospital), Xi'an, China

Synopsis

Keywords: Functional Connectivity, Psychiatric Disorders, Dynamic functional connectivity, Triple Network, White matter functional network, coupling

Motivation: The brain functional alterations in schizophrenia and the impact of antipsychotic medication on brain function remain unclear.

Goal(s): To explore the changes in the triple network and white matter functional networks in patients with schizophrenia, as well as the variations observed during longitudinal follow-up after treatment.

Approach: A sliding window approach was used to analyze the dynamic functional connectivity (FC) of the triple network and white matter, as well as the global coupling between them.

Results: Schizophrenia patients showed alterations in the dynamic FC within networks, as well as in their temporal characteristics, which exhibited dynamic changes over the follow-up period.

Impact: These findings highlight the importance of dynamic FC and functional coupling between the triple network and white matter in the pathogenesis of schizophrenia, which may aid in a better comprehension of the dynamic changes within the disease networks.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords