Meeting Banner
Abstract #2515

The impact of postural changes on resting-state functional connectivity in healthy brains based on mutli-position helium-free MRI

Yukun Zhang1, Rongfeng Qi2, and Bing Zhang2
1Department of Radiology, Nanjing Drum Tower Hospital, School of Social Sciences,Nanjing University, Nanjing, China, 2Department of Radiology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China

Synopsis

Keywords: Functional Connectivity, fMRI (resting state)

Motivation: An important but underexplored confound in fMRI is body posture.

Goal(s): Exploring the Impact of Standing and Lying Positions on Brain Resting-State Functional Connectivity Imaging.

Approach: 29 healthy volunteers underwent multi-position helium-free 1.5T MRI (XGY Spin 1.5T MRI) scans. The scan sequences included upright fMRI and supine 3D T1WI and fMRI. A comparison of functional connectivity metrics between the upright and supine fMRI was conducted.

Results: Compared to the supine position, the ALFF values of multiple brain regions were altered in the upright position. The upright position led to changes in whole-brain and default mode network (DMN) connectivity compared to the supine position.

Impact: Multi-position helium-free 1.5T MRI helps investigate the functional states of various diseases in daily upright posture. It opens a new chapter in brain science research.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords