Keywords: Functional Connectivity, fMRI (resting state)
Motivation: An important but underexplored confound in fMRI is body posture.
Goal(s): Exploring the Impact of Standing and Lying Positions on Brain Resting-State Functional Connectivity Imaging.
Approach: 29 healthy volunteers underwent multi-position helium-free 1.5T MRI (XGY Spin 1.5T MRI) scans. The scan sequences included upright fMRI and supine 3D T1WI and fMRI. A comparison of functional connectivity metrics between the upright and supine fMRI was conducted.
Results: Compared to the supine position, the ALFF values of multiple brain regions were altered in the upright position. The upright position led to changes in whole-brain and default mode network (DMN) connectivity compared to the supine position.
Impact: Multi-position helium-free 1.5T MRI helps investigate the functional states of various diseases in daily upright posture. It opens a new chapter in brain science research.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords