Keywords: Tumors (Post-Treatment), Tumors, brain tumor, gamma knife radiosurgery, assessment of treatment toxicity, optic pathways
Motivation: Gamma Knife radiosurgery (GKRS) for sellar tumors risks radiation exposure to critical optic pathways. This study investigates the possible GKRS-induced microstructural changes and thereby assessing treatment toxicity.
Goal(s): Gamma Knife radiosurgery (GKRS) for sellar tumors risks radiation exposure to critical optic pathways. This study investigates the possible GKRS-induced microstructural changes and thereby assessing treatment toxicity.
Approach: Gamma Knife radiosurgery (GKRS) for sellar tumors risks radiation exposure to critical optic pathways. This study investigates the possible GKRS-induced microstructural changes and thereby assessing treatment toxicity.
Results: TBSS and VBA analyses showed no significant microstructural changes in multiple DTI parameters within the optic radiation.
Impact: Advanced DTI analysis with TBSS and VBA confirms that GKRS preserves optic radiation integrity in sellar tumor patients. Future studies can extend these methods to assessing long-term radiation effects on neural pathways and refining neuroprotective strategies in radiotherapy.
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