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Abstract #2544

Differentiation of Postoperative Recurrence and Pseudoprogression of Gliomas Using Multi-b Value Diffusion-Weighted Imaging

Jiaxuan Zhang1, Peiquan Liu1, Ning Zheng2, and Wenzhen Zhu1
1Department of Radiology, Tongji Hospital, Tongji Medical College,Huazhong University of Science and Technology, Wuhan, China., Wuhan City, China, 2Clinical & Technical Support, Philips Healthcare, China., Wuhan City, China

Synopsis

Keywords: Tumors (Post-Treatment), Neuro

Motivation: The ability to distinguish between postoperative recurrence and pseudoprogression (PsP) in glioma patients is crucial for guiding subsequent treatment strategies.

Goal(s): This study aims to evaluate whether six diffusion models derived from multi-b value diffusion-weighted imaging (DWI) can accurately differentiate PsP and true recurrence (TR) in glioma patients.

Approach: A total of 66 postoperative glioma patients underwent imaging multi-b value DWI at 3.0T MRI. Post-processing yielded 14 parameter maps from the six diffusion models based on multi-b value DWI.

Results: Receiver operating characteristic (ROC) analysis of these parameters indicated that FROC_D is the optimal parameter for distinguish TR and PsP.

Impact: This study employed various diffusion models to conduct a preliminary analysis of the discriminative value of multi-b-value DWI techniques in the postoperative assessment of gliomas, providing a reference for the selection of diffusion models in subsequent clinical diagnosis and treatment.

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