Abstract #2584

Improved Brain Tumor Visualization with 3T Stack-of-Stars Echo Unbalanced T1 Relaxation-Enhanced Steady-State MRI – A Two Center Clinical Study

Adrienn Tóth¹, Robert R Edelman^2,3, Justin A Chetta¹, Jennifer Joyce¹, Jonathan Eernisse¹, Ruoxun Zi⁴, Kai Tobias Block⁴, Maria Vittoria Spampinato¹, and Akos Varga-Szemes¹

¹Department of Radiology and Radiological Science, Medical University of South Carolina, Charleston, SC, United States, ²Department of Radiology, NorthShore University Health System, Evanston, IL, United States, ³Department of Radiology, Feinberg School of Medicine, Chicago, IL, United States, ⁴Department of Radiology, The Bernard and Irene Schwartz Center for Biomedical Imaging, New York University Grossman School of Medicine, New York, NY, United States

Synopsis

Keywords: Pulse Sequence Design, Acquisition Methods

Motivation: The echo unbalanced T1 relaxation-enhanced steady-state (echo-uT1RESS) technique offers strong dark-blood effect; however, its effectiveness is compromised by sensitivity to head motion, motivating the development of a motion-resistant version using radial stack-of-stars (SOS) k-space trajectory.

Goal(s): To assess the diagnostic performance of the SOS echo-uT1RESS technique in comparison to magnetization-prepared rapid gradient echo (MPRAGE).

Approach: A two-center prospective study was conducted involving 25 patients, utilizing both quantitative and qualitative analyses of post-contrast acquisitions.

Results: The SOS echo-uT1RESS technique improved tumor-to-brain contrast and lesion conspicuity while maintaining high image quality and comparable artifact levels.

Impact: This study highlights the SOS echo-uT1RESS technique's potential to significantly improve visualization and characterization of brain lesions. It offers consistent dark-blood effect and improved lesion conspicuity, while maintaining high image quality and motion robustness, with promising implications for clinical practice.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.