Keywords: Data Acquisition, Lung, PREFUL, Pulmonary Proton MRI, Sequence
Motivation: Free breathing pulmonary proton MRI gained interest during the last years. The next important step for method validation is the conduction of multicenter studies.
Goal(s): As exact MRI sequence implementation depends on the vendor, a pulse sequence developed with a framework with multi-vendor support as Pulseq, sequence-related variability can be mitigated.
Approach: A spoiled gradient echo sequence (SPGRE) was optimized for Phase-Resolved functional lung (PREFUL) MRI. The settings were adapted to be in alignment with a Siemens FLASH sequence used in previous studies.
Results: All PREFUL parameters showed no significant differences between Siemens FLASH and Pulseq SPGRE implementation in 9 healthy volunteers.
Impact: The demonstrated sequence can be easily shared between centers to homogenize the data acquisition for functional lung imaging with PREFUL and similar methods. The reduction of sequence-related variability, may lead to substantial improvement of reproducibility and comparability between centers.
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