Keywords: Signal Modeling, MSK, UTE imaging, bone imaging
Motivation: Cortical bone has two distinct water components: pore water and bound water. Pore water reflects cortical porosity, while bound water is related to organic matrix density.
Goal(s): To develop fast MRI technique to map bound and pore water in cortical bone.
Approach: The rapid dual-component ultrashort echo time (RaD-UTE) technique employs 3D UTE multi-echo acquisitions for fast volumetric mapping of bound and pore water, including their T1 and T2*s relaxation times as well as T1-corrected bound and pore water fractions.
Results: RaD-UTE allows fast volumetric mapping of bound and pore water T2*, T1, and T1-compensated fractions.
Impact: The RaD-UTE technique allows fast volumetric mapping of bound and pore water T1, T2*s, and fractions, and has great potential for accurate mapping of cortical porosity and organic matrix density under clinical acceptable scan time.
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