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Abstract #2613

Initial Experience of Carotid Artery MR Vessel Wall imaging at 5.0T

Qinxin Wang1, Xihai Zhao1, Huiyu Qiao2, Ning Xu1, and Decheng Meng3
1Center for Biomedical Imaging Research, School of Biomedical Engineering, Tsinghua University, Beijing, China, Beijing, China, 2School of Biomedical Engineering, Capital Medical University, Beijing, China, Beijing, China, 3Department of Radiology, Peking University Third Hospital, Beijing, China, Beijing, China

Synopsis

Keywords: Data Acquisition, Data Acquisition, Carotid Artery Imaging, 5.0T MRI, Vessel Wall Imaging, Signal-to-Noise Ratio (SNR), Contrast-to-Noise Ratio (CNR), Atherosclerotic Plaque

Motivation: Carotid artery plaque rupture is a major cause of ischemic stroke, making accurate plaque assessment crucial for prevention. Current 3.0T MR imaging lacks sufficient spatial resolution for detailed plaque analysis, motivating exploration at 5.0T.

Goal(s): To evaluate the advantages of 5.0T MR imaging for carotid vessel wall visualization and precise evaluation of the plaque components.

Approach: The study compared vessel wall imaging at 3.0T and 5.0T in healthy volunteers and patients, using multi-contrast sequences and different spatial resolutions.

Results: 5.0T significantly enhances image quality, with improved plaque visualization and black blood uniformity, affirming its potential for precise plaque characterization.

Impact: This study demonstrates that 5.0T MR imaging significantly enhances carotid plaque visualization, potentially aiding clinicians in early stroke risk assessment. The findings facilitate future studies on ultra-high field MRI’s role in diagnosing vulnerable plaque, advancing preventative stroke care.

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Keywords