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Abstract #2658

Pancreatic T1, T2, T2* and PDFF values in healthy pancreas and spectrum of pancreatitis

Monica Gunasingh1,2, Nikhil Suryadevara3, Suvarna Naidu3, Tharani Putta3, Sashidhar Kaza3, Jithin Sreekumar2, and Jaladhar Neelavalli2
1Philips India Limited, Chennai, India, 2Department of Biomedical Engineering, Indian Institute of Technology, Hyderabad, India, 3Department of Radiology, Asian Institute of Gastroenterology, Hyderabad, India

Synopsis

Keywords: Pancreas, Pancreas, Pancreatitis, Relaxometry, T1, T2, T2*, PDFF

Motivation: To gain a better understanding of the change in tissue micro-structural properties in healthy and diseased pancreas

Goal(s): To study the quantitative MR parameters of pancreas in patients with acute pancreatitis, chronic pancreatitis vs normal group

Approach: T1, T2, T2* and PDFF values of the pancreas in patients with Acute Pancreatitis, Chronic Pancreatitis, normal subjects and subjects with normal pancreas who had prior history of pancreatitis were measured prospectively

Results: The T1 and T2 values showed significant difference between the groups. No difference was observed between the normal and normal with prior history of pancreatitis groups

Impact: Multiparametric MRI of pancreas can reveal tissue properties which are not apparent to the naked eye on conventional MRI sequences, and can help assess pancreatic health, identify subclinical disease, and potentially predict the nature course of illness.

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Keywords