Meeting Banner
Abstract #2660

Fat quantification map facilitates intra-tumoral microscopic fat visualization, detection and quantification

Lu Xu1, Yihong Zhong1, Wei Cui2, Dehong Luo1, and Zhou Liu1
1Department of Radiology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 113 Baohe Avenue, 518116, Shenzhen, China, Shenzhen, China, 2GE Healthcare, MR Research China, Beijing, China, Beijing, China

Synopsis

Keywords: Kidney, Quantitative Susceptibility mapping

Motivation: The identification of microscopic fat by chemical shift imaging through signal reduction on out-phase is diagnostically significant in differentiating angiomyolipoma (AML) from renal cell carcinoma (RCC).

Goal(s): This study evaluated the efficacy of fat quantification maps in detecting intra-tumoral microscopic fat and using histogram-based quantitative parameters to differentiate RCC from AML.

Approach: The results demonstrated that fat quantification maps significantly reduce inter-observer variability in evaluating lesional fat content. Additionally, RCC and AML showed distinct intensity distribution patterns based on histogram-derived parameters.

Results: These findings confirm that fat quantification maps, combined with quantitative measurements, effectively aid in the differential diagnosis of AML and RCC.

Impact: Fat-quantification maps can improve the indentification and quantification of microscopic fat, enhancing differentiation of angiomyolipoma and renal cell carcinoma, which can be integrated seamlessly into clinical workflows for a systematic approach.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords