Abstract #2706

Three-dimensional T1 mapping for whole renal MRI by multiple inversion-time samplings look-locker sequence (mTI-LL)

wenyan zhang^1,2, Zelong Chen³, Quan Tao^2,4, Yizhe Zhang ^1,2, Yikai Xu³, and Yanqiu Feng ^1,2,5,6

¹School of Biomedical Engineering, School of Biomedical Engineering, Southern Medical University, GuangZhou, China, ²Guangdong Provincial Key Laboratory of Medical Image Processing & Guangdong Province Engineering Laboratory for Medical Imaging and Diagnostic Technology, Southern Medical University, Guangzhou, China, ³Medical Imaging Center, Nanfang Hospital, Southern Medical University, Guangzhou, China, ⁴Department of Rehabilitation Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou, China, ⁵Guangdong-Hong Kong-Macao Greater Bay Area Center for Brain Science and Brain-Inspired Intelligence & Key Laboratory of Mental Health of the Ministry of Education & Guangdong-Hong Kong Joint Laboratory for Psychiatric Disorders, Southern Medical University, Guangzhou, China, ⁶Department of Radiology, Shunde Hospital,Southern Medical University (The First People's Hospital of Shunde, Foshan), Foshan, China

Synopsis

Keywords: Kidney, Quantitative Imaging, T1 mapping

Motivation: Limited coverage and low resolution limit clinical application of renal T1 mapping.

Goal(s): We aimed to develop a fast and high resolution 3D T1 mapping sequence for kidney imaging.

Approach: The multiple inversion-time samplings look-locker sequence (mTI-LL) was implemented, using a simplified Bloch simulation for signal fitting. This technique was tested on volunteers and compared to the conventional Modified Look‐Locker inversion recovery(2D-MOLLI).

Results: Compared 2D-MOLLI, mTI-LL offers higher resolution and greater coverage within a clinically acceptable scan time.

Impact: The mTI-LL technique showed great potential for clinical applications,it appropriate for 3D T1 mapping with whole-kidney coverage and high-resolution.

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