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Abstract #2760

Whole Brain Magnetic Susceptibility Mapping at 0.3 mm Isotropic Mesoscale Resolution with Motion and B0-shift Corrections at 7T

Yuguang Meng1, Ibraheem Budeir1, and Deqiang Qiu1,2
1Department of Radiology and Imaging Sciences, Emory University, Atlanta, GA, United States, 2Department of Biomedical Engineering, Emory University and Georgia Institute of Technology, Atlanta, GA, United States

Synopsis

Keywords: Motion Correction, Motion Correction

Motivation: High-resolution quantitative susceptibility mapping (QSM) is challenging at high magnetic field as the quality of GRE images is susceptible to both motion and B0 field change with motion.

Goal(s): To investigate the feasibility of whole brain QSM at an isotropic 0.3 mm resolution with motion and B0-shift corrections at 7T.

Approach: A recently developed method of using dual-echoes spiral navigators and conjugate-phase reconstruction.

Results: The motion and B0-shift sensitivities in mesoscale resolution can be effectively reduced by corrections with the simple and parallelizable conjugate-phase reconstruction in long scan.

Impact: High-quality mesoscale whole brain QSM with the developed method provides a reliable tool for assessing neurodegenerations.

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Keywords