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Abstract #2804

Does cine-dynamic MRCP at 1.5T vs. 3.0T differ in noninvasively assessing pancreatic exocrine function under physiological conditions?

Qiaoling Wu1, Jingyi Liu1, Dandan Zheng2, and Huadan Xue1
1Department of Radiology, Peking Union Medical College Hospital, Beijing, China, 2Clinical & Technique Support, Philips Healthcare, Beijing, China

Synopsis

Keywords: Pancreas, Bioeffects & Magnetic Fields, Pancreatic Exocrine, Cine-dynamic MRCP

Motivation: Pancreatic secretion flow is key to assessing pancreatic exocrine function, and cine-dynamic MRCP showing potential for tracking changes in secretion flow.

Goal(s): To compare 1.5T and 3.0T cine-dynamic MRCP in evaluating pancreatic exocrine function.

Approach: Cine-dynamic MRCP was conducted on 36 healthy volunteers before and after an oral fatty meal. The differences between the lengths and frequencies of pancreatic juice secretion were compared using Independent-Samples T-Test, and the change post-meal at each field strength was also compared using Paired-Samples T-Test.

Results: Both 1.5T and 3.0T showed increased secretion frequency and length of pancreatic juice post-meal, with no significant differences between the field strengths.

Impact: This study demonstrated that the feasibility of cine-dynamic MRCP for assessment of pancreatic exocrine physiological function change at both 1.5T and 3.0T. The frequency and length of pancreatic secretion observed shows good agreement between 1.5T and 3.0T.

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