Keywords: Digestive, Quantitative Imaging, Magnetic resonance imaging; mucinous adenocarcinoma; rectal cancer; T1-mapping
Motivation: Differentiating mucinous adenocarcinoma (MC) from adenocarcinoma not otherwise specified (AC) is crucial due to distinct prognostic and treatment responses.
Goal(s): To assess high-spatial-resolution T2-weighted imaging (HR-T2WI) and T1-mapping effectiveness in distinguishing MC from AC in rectal cancer.
Approach: In this prospective study of 92 patients (55 AC, 37 MC), radiologists assessed HR-T2WI scans, and pre- and post-contrast T1 relaxation times were measured. Diagnostic efficacy was evaluated using receiver operating characteristic curve analysis.
Results: HR-T2WI achieved 81.08% sensitivity and 94.55% specificity. The combined HR-T2WI and T1p model yielded a 0.927 area under the curve, improving diagnostic performance over individual techniques
Impact: This study suggests combining HR-T2WI and T1-mapping as a non-invasive method for diagnosing MC in rectal cancer, potentially reducing false-negative biopsies. Future research can explore its role in treatment response prediction and outcome assessment.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords