Abstract #2831

Improved Characterization of Liver Lesions with Hepatobiliary Phase Free-Breathing, Phase Sensitive Inversion Recovery MRI

Yavuz Muslu^1,2, Julius Frederik Heidenreich¹, Jan-Peter Grunz¹, Ty A Cashen², Sagar Mandava², Ali Pirasteh^1,3, Diego Hernando^1,3,4,5, and Scott B Reeder^1,3,4,6,7

¹Department of Radiology, University of Wisconsin-Madison, Madison, WI, United States, ²GE HealthCare, Waukesha, WI, United States, ³Department of Medical Physics, University of Wisconsin-Madison, Madison, WI, United States, ⁴Department of Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, United States, ⁵Department of Electrical and Computer Engineering, University of Wisconsin-Madison, Madison, WI, United States, ⁶Department of Medicine, University of Wisconsin-Madison, Madison, WI, United States, ⁷Department of Emergency Medicine, University of Wisconsin-Madison, Madison, WI, United States

Synopsis

Keywords: Liver, Liver

Motivation: Gadoxetic acid enhanced T₁ weighted (T₁w) MRI is widely used for the detection of liver lesions. However, it is inadequate for lesion characterization due to poor contrast variation among lesions. Enhancing T₁ contrast may enable simultaneous detection and characterization of lesions using a single T₁w sequence.

Goal(s): To demonstrate improved lesion characterization with phase sensitive inversion recovery (PSIR) T₁w MRI.

Approach: Forty patients were imaged prospectively using a free-breathing PSIR T₁w sequence at 1.5T and 3.0T. Image quality and lesion-to-liver contrast were compared to conventional navigated spoiled gradient echo (SGRE) T₁w imaging.

Results: PSIR-T₁w showed improved lesion visualization compared to SGRE T₁w.

Impact: GA-enhanced PSIR-T₁w MRI improves T₁ contrast and offers variable T₁w imaging in a single acquisition, enabling both detection and characterization of lesions with a single T₁w image acquisition.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.