Meeting Banner
Abstract #2851

Preoperative Liver Function Assessment in Biliary Tract Cancer Patients Using Routine Clinical DCE-MRI: A Prospective Study

Xiaoqi Lin1, Ming Xiao2,3, Ziming Xu1, Haozhong Sun1, Yajie Wang1, Shuwan Yu1, Canhong Xiang3, Jiahong Dong3, and Huijun Chen1
1Department of Biomedical Engineering, Tsinghua University, Beijing, China, 2Department of Hepatobiliary Surgery, The Second Hospital of Shandong University, Shandong, China, 3Hepatopancreatobiliary Center, Beijing Tsinghua Changgung Hospital, Key Laboratory of Digital Intelligence Hepatology (Ministry of Education), School of Clinical Medicine, Tsinghua University, Beijing, China

Synopsis

Keywords: Hepatobiliary, DSC & DCE Perfusion, Biliary Tract Cancer patient risk assessment

Motivation: Biliary tract cancers (BTC) requiring extensive liver resections lack sufficient methods of functional evaluation. DCE-MRI derived functional parameters are promising imaging biomarkers for regional liver function evaluation.

Goal(s): This study addresses the demand for accurate preoperative functional evaluation and risk assessment in BTC patients undergoing liver resection.

Approach: We compared the correlations between functional imaging biomarkers and blood serum markers. By combining functional imaging biomarkers with traditional markers, we built a machine learning model for postoperative complication prediction.

Results: We illustrated correlations between functional imaging biomarkers and blood serum markers and the prediction model had an AUC of 0.784.

Impact: Our work enhances preoperative risk assessment in biliary tract cancer by integrating MRI-derived functional parameters with serum markers, complementing traditional metrics for more accurate regional liver function evaluation and improving prediction of postoperative complications for personalized surgical planning.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords