Keywords: Functional Connectivity, fMRI (resting state)
Motivation: In patients with Chronic Back Pain (CBP), rs-fMRI signals in the cerebral cortex may exhibit frequency dependency and temporal variability.
Goal(s): To explore potential changes in functional connectivity in patients with CBP and to determine whether these alterations vary across different frequency bands and dynamic indicators.
Approach: In patients with CBP, changes in functional connectivity were analyzed using traditional Degree Centrality (DC), DC in subfrequency bands (slow-5, slow-4), and dynamic Degree Centrality (dDC).
Results: In CBP patients, functional connectivity changes were observed across multiple brain regions, with additional areas identified in the slow-5 frequency band and dynamic DC compared to traditional DC.
Impact: This study demonstrates that incorporating frequency and dynamic analysis in addition to traditional DC metrics can better understand the functional characteristics of the brain in CBP.
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