Abstract #2884

Motion-robust, time-efficient, whole-liver DWI using Diffusion PLUS (Physiology-Led Unique Slice ordering)

Masami Yoneyama¹, Daichi Murayama², Takayuki Sakai^2,3,4, Yasuhiro Goto⁵, Michinobu Nagao⁶, Jip F Prince⁷, Niels Blanken⁷, Shuo Zhang⁸, Iain Ball⁹, Marc Van Cauteren¹, and Johannes M Peeters⁸

¹Philips Japan, Tokyo, Japan, ²Radiology, Eastern Chiba Medical Center, Chiba, Japan, ³Faculty of Health Sciences, Tsukuba International University, Ibaraki, Japan, ⁴Kanazawa University, Ishikawa, Japan, ⁵Department of Radiological Services, Tokyo Women’s Medical University, Tokyo, Japan, ⁶Department of Diagnostic Imaging and Nuclear Medicine, Tokyo Women’s Medical University, Tokyo, Japan, ⁷Department of Radiology, University Medical Center Utrecht, Utrecht, Netherlands, ⁸Philips Healthcare, Best, Netherlands, ⁹Philips Australia & New Zealand, North Ryde, Australia

Synopsis

Keywords: Liver, Liver, Diffusion

Motivation: Cardiac motion affects liver DWI, particularly in the left lobe, leading to signal loss and overestimation of ADC values. Current solutions are either time-consuming or compromise image quality.

Goal(s): To develop and evaluate Diffusion PLUS, a novel DWI sequence that improves motion robustness while reducing scan time

Approach: The Diffusion PLUS technique employs optimized slice ordering and physiology-led triggering to address both cardiac and respiratory motion in liver DWI without prolonging TE.

Results: Diffusion PLUS achieved motion-robust, whole-liver DWI with clinically feasible scan times, offering a promising alternative for routine liver pathology assessments.

Impact: Diffusion PLUS improves liver DWI by providing fast scans with reliable image quality. It offers a practical option in the clinical environment and may enhance diagnostic accuracy for liver lesions, particularly in the left lobe.

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