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Abstract #2891

Diagnostic and predictive potential of multiple b-value DWI for allograft dysfunction after kidney transplantation during follow-up

Lihua Chen1, Ping Yang1, Jianmin Cui2, Shuangshuang Xie1, Yujun Lu3, Dandan Sun1, Jinxia Zhu4, and Robert Grimm5
1Tianjin First Central Hospital, Tianjin, China, 2Tianjin Medical University General Hospital, Tianjin, China, 3Tianjin Occupational Diseases Precaution and Therapeutic Hospital, Tianjin, China, 4Siemens Healthineers, Beijing, China, 5Siemens Healthineers AG, Forchheim, Germany

Synopsis

Keywords: Kidney, Kidney, Kidney transplantation, Follow-up, Allograft function

Motivation: Early estimate and monitor of renal function are important to guide clinical intervention and reduce complications. DWI as a noninvasive technique is considered to be a powerful tool for evaluating and longitudinal follow-up of kidney allograft function.

Goal(s): To evaluate the ability of multi-b-value DWI to follow-up monitor function and predict allograft dysfuction.

Approach: The diffusion parameters of allograft generated from multi-b-value DWI at 14d, 30d, 90d after kidney tranplantation were obtained. eGFR during follow-up were collected.

Results: Multiple b-value DWI provides a useful tool for noninvasive longitudinal follow-up allograft function, and the parameters early after transplantation can predict allograft dysfunction.

Impact: The parameters generated from multi-b-value DWI may help to improve the monitoring ability for follow-up of allograft function. The parameters in the early stage can provide a certain complementary role for predict dysfunction and adjustment of the follow-up program.

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Keywords