Keywords: Pancreas, DWI/DTI/DKI
Motivation: Clinically relevant postoperative pancreatic fistula (CR-POPF) is one of the most threatening complications after pancreatoduodenectomy, and there remains challenging to accurate predict CR-POPF preoperatively.
Goal(s): To investigate the value of continuous-time random-walk (CTRW) and virtual MR elastography (vMRE) in predicting CR-POPF after pancreatoduodenectomy in pancreatic ductal adenocarcinoma.
Approach: Independent quantitative parameter from CTRW and vMRE associated with CR-POPF were identified, and a combined prediction model were built.
Results: CTRW_β (OR = 7223.62), CTRW_Dm (OR = 3117.57), and vMRE_μDiff (OR = 6.60) were independent preoperative predictors of CR-POPF (all p < 0.05). The combined model demonstrated satisfied performance with an AUC of 0.866.
Impact: Non-Gaussian diffusion model CTRW and vMRE techniques exhibited the ability in predicting CR-POPF preoperatively, and their combination could improve the predictive performance. Our prediction model may help clinicians adopt appropriate prevention or mitigation strategies to reduce the probability of CR-POPF.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords