Keywords: Spectroscopy, Brain, Lipid, MRSI, rat, spectroscopic imaging
Motivation: Robust and efficient solutions are needed to accurately remove lipid signals for fast 1H-MRSI in the rodent brain while preserving the metabolite signals.
Goal(s): Analyze the effects of retrospective lipid suppression on metabolite estimates at 14.1T in the rat brain for 1H-FID-MRSI.
Approach: SVD-based lipid suppression was applied for retrospective lipid suppression.
Results: Overall, the retrospective lipid suppression is slightly influencing the metabolite concentration estimates in the rat brain for 1H-FID-MRSI at 14.1T.
Impact: Our work is evaluating the retrospective lipid suppression on metabolite estimates at 14.1T in the rat brain for 1H-FID-MRSI. When using low lipid contaminated data, an effect on concentration estimates was observed, highlighting the need for future investigations.
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