Abstract #2964

Effect of Cerebellar tDCS on Postural Control and Neuroplastic Changes in Chronic Ankle Instability

Rong Lu¹, Xiao’ao Xue², Shanshan Zheng³, Yuwen Zhang⁴, Tian Xia², Tingfang Hwang¹, Ying-Hua Chu⁵, Qing Li⁵, Weijun Tang¹, Yinghui Hua², and He Wang^6,7,8

¹Department of Radiology, Huashan Hospital, Fudan University, Shanghai, China, ²Department of Sports Medicine, Huashan Hospital, Fudan University, Shanghai, China, ³Department of Sports Medicine, School of Exercise and Health, Shanghai University of Sport, Shanghai, China, ⁴Institute of Science and Technology for Brain-Inspired Intelligence, Fudan Universit, Shanghai, China, ⁵MR Research Collaboration, Siemens Healthineers Ltd., Shanghai, China, ⁶Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China, ⁷Human Phenome Institute, Fudan University, Shanghai, China, ⁸Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence (Fudan University), Ministry of Education, Shanghai, China

Synopsis

Keywords: Functional/Dynamic, Neuroscience, prolactinoma

Motivation: We aimed to activate cerebellar functions and evaluate its effect on postural control and associated neuroplastic alternations in chronic ankle instability(CAI).

Goal(s): Postural control impairment, a key feature of CAI, is crucial for daily and sports activities but lacks effective treatment strategies. Recent evidence links maladaptive neuroplasticity in the cerebellum to these deficits.

Approach: Consecutive CAI participants were assigned to sham or active groups for cerebellar anodal tDCS in a preliminary randomized controlled trial.

Results: Our study showed that a single cerebellar tDCS session improved postural control in CAI patients and increased coherence in the cerebellum's superior lobe.

Impact: This preliminary study marks the first application of cerebellar tDCS in the rehabilitation of CAI and musculoskeletal injuries.

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