Keywords: Lung, Lung, Pulmonary embolism
Motivation: Antithrombotic treatment of patients with pulmonary embolism (PE) is not monitored routinely and treatment effectiveness is often unknown.
Goal(s): Our goal was to assess the feasibility of arterial spin labeling (ASL) MRI to monitor treatment effects in patients with PE.
Approach: 15 patients of initially 107 patients with PE underwent follow-up imaging with ASL-MRI.
Results: A significant improvement in perfusion was observed in all patients after treatment. 8 of 15 patients showed remaining pulmonary perfusion defects. There was a significant correlation between remaining dyspnea and the detection of perfusion defects after treatment.
Impact: Arterial spin labeling (ASL)- MRI demonstrates the potential to monitor pulmonary perfusion changes in patients with pulmonary embolism under therapy.
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