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Abstract #3050

Optimised Reduced Field of View and Fat Suppression Techniques in Interleaved Multi-slice Diffusion Tensor Cardiovascular Magnetic Resonance

Yaqing Luo1,2,3, Pedro F. Ferreira1,2, Dudley J. Pennell1,2, Guang Yang2,4, Sonia Nielles-Vallespin1,2, and Andrew D. Scott1,2
1National Heart and Lung Institute, Imperial College London, London, United Kingdom, 2CMR Unit, Royal Brompton Hospital, London, United Kingdom, 3EPSRC Centre for Doctoral Training in Smart Medical Imaging, King’s College London and Imperial College London, London, United Kingdom, 4Bioengineering Department and Imperial-X, Imperial College London, London, United Kingdom

Synopsis

Keywords: Myocardium, Acquisition Methods, Diffusion Acquisition, Myocardium, Cardiovascular, Fat Suppression, Reduced FOV

Motivation: A reduced Phase Encoding (PE) FOV is often used to reduce artefacts in Diffusion Tensor Cardiovascular Magnetic Resonance (DT-CMR) and effective fat suppression is important to avoid problematic displaced fat signals.

Goal(s): To assess and optimise the performance of reduced PE FOV and fat suppression techniques on interleaved multi-slice Spin Echo (SE) DT-CMR.

Approach: Four reduced PE FOV techniques and three fat suppression techniques were implemented and compared in 6 subjects.

Results: The flip-back sequence and binomial water selective excitation are effective and complimentary methods of suppressing signals outside the desired FOV and originating from fat in multi-slice DT-CMR.

Impact: Robust fat suppression provided by binomial water selective excitation in combination with reduced phase FOV DT-CMR compatible with interleaved multi-slice imaging, will enable efficient spin echo based assessment of the cardiac microstructure in future clinical studies.

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Keywords