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Abstract #3110

Evaluation of 3.0T MR IDEAL-IQ for fat fraction and T2 * value to diagnose osteoporosis

Yan Zhang1, Ze Li1, Xihan Xiang1, Yuchen Liu2, and Junrong Chen3
1Chengdu Sports University, Chengdu Sichuan, China, 2GE HealthCare MR Research, Beijing, China, 3Sichuan Province Orthopedic Hospital, Chengdu Sichuan, China

Synopsis

Keywords: Bone/Skeletal, Bone

Motivation: Existing studies have focused on a single parameter, fat fraction (FF) or T2* value, to assess osteoporosis with low diagnostic efficacy.

Goal(s): The study aimed to evaluate the efficacy of FF,T2* value, and their combination in diagnosing osteoporosis.

Approach: The IDEAL IQ MR sequence was used to measure the FF and T2*value of the vertebral, and quantitative computed tomography was used to measure vBMD.

Results: Significant discrimination in FF and T2* value were found between normal individuals and osteoporotic patients, and the efficacy of the combination of FF and T2* for the diagnosis of osteoporosis was superior to that of a single indicator.

Impact: MRI-based FF and T2* value can be used as a supplement to BMD for early assessment of fracture risk to prevent fragility fractures.

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