Meeting Banner
Abstract #3129

MRE-Derived Stiffness Measurements of Painful and Non-Painful Discs from Low Back Pain Patients

Zachary Ryan Osborn-King1, Megan Co1, Tristan Weaver2, Nasir Hussain3, Brian Raterman4, Arunark Kolipaka4, and Benjamin A. Walter1
1Biomedical Engineering, The Ohio State University College of Engineering, Columbus, OH, United States, 2Anesthesiology, The Ohio State University College of Medicine, Columbu, OH, United States, 3Anesthesiology, The Ohio State University College of Medicine, Columbus, OH, United States, 4Radiology, The Ohio State University College of Medicine, Columbus, OH, United States

Synopsis

Keywords: Cartilage, Elastography

Motivation: No prior work has used Magnetic Resonance Elastography to determine if mechanical parameters can be used to differentiate between painful and non-painful discs in Low Back Pain patients.

Goal(s): To determine if there are differences in the mechanical and compositional properties of painful and non-painful discs from the same patient.

Approach: Seventeen patients were recruited from the clinic and had MRE, T1rho, and T2 done on a clinically diagnosed painful and non-painful disc.

Results: Stiffness parameters were significantly stiffer for painful discs, T2 compositional parameter showed significantly higher water content in non-painful discs, and a trend towards increased T1rho in non-painful discs.

Impact: Developing a method to objectively measure tissue stiffness, demonstrating there are mechanical differences in painful discs compared to non-painful controls, and demonstrating compositional differences between these groups allows clinicians and researchers to have more tools to assess low back pain

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords