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Abstract #3131

Added Value of 3D Fast-field-echo (FRACTURE) Sequences for Cervical Spondylosis Diagnosis: A Prospective Multi-Reader Non-Inferiority Study

Qizheng Wang1, Ning Lang1, Xiaoying Xing1, Shipei He2, and Yuxin Yang2
1Peking University Third Hospital, Beijing, China, 2United Imaging Research Institute of Intelligent Imaging, Beijing, PR China, Beijing, China

Synopsis

Keywords: Bone/Skeletal, Pulse Sequence Design

Motivation: MRI is still insufficient in the evaluation of bone abnormalities.

Goal(s): To assess the diagnostic performance of fast field echo resembling a CT using restricted echo-spacing (FRACTURE) in detecting cervical bone abnormalities.

Approach: 137 consecutive patients with cervical spondylosis were continuously enrolled. CT, routine MRI and 3D-FRACTURE sequences were performed. Three radiologists independently evaluated osteophytes, bony foraminal stenosis, posterior longitudinal ligament ossification (OPLL).

Results: Good to excellent inter-rater reliability for FRACTURE with CT (osteophytes: ICC, 0.83–1.00; OPLL: ICC, 0.73–0.92; bony foraminal stenosis: ICC, 0.76–0.98), which was superior to conventional MRI.FRACTURE passed the non-inferiority test within a margin of 0.5 with higher diagnostic confidence.

Impact: The FRACTURE protocol demonstrated comparable performance to CT in assessing bone abnormalities in cervical spondylosis, offering the potential to reduce radiation exposure and streamline the diagnostic process for patients.

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Keywords