Abstract #3167

Association of Choroid Plexus Volume and Preeclampsia：A Research Based on Magnetic Resonance Imaging

Boyao Chen¹, Linfeng Yang², Tao Chen³, Meng Li⁴, Lingfei Guo⁵, Na Wang⁵, Xinyue Zhang⁵, Yuanyuan Wang⁶, Zhenyu Cheng⁷, Pengcheng Liang⁵, Yiwen Chen⁵, Xinxin Huo⁵, and Fushuai Zhang⁷

¹Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, Jinan, China, China, ²Jinan Maternity and Child Care Hospital Affiliated to Shandong First Medical University, Jinan, Shandong Province, China, Jinan, China, China, ³Department of Clinical laboratory, Jinan Maternity and Child Care Hospital Affiliated to Shandong First Medical University, Jinan 250001, Shandong Province, China, Jinan, China, China, ⁴Department of Psychiatry and Psychotherapy, Jena University Hospital, Jena, Germany, Jena, Germany, ⁵shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China, Jinan, China, China, ⁶School of Medical Imaging，Binzhou medical university,Yantai,Shandong,China, Yan, China, China, ⁷School of Medical Imaging，Binzhou medical university,Yantai,Shandong,China, Yantai, China

Synopsis

Keywords: Other Neurodegeneration, Brain, Choroid plexus volume, Preeclampsia, Glymphatic system, Quantitative susceptibility mapping

Motivation: This study aims to investigate alterations in choroid plexus volume (CPV) and susceptibility values of the choroid plexus obtained from quantitative susceptibility mapping (QSM) in patients with preeclampsia, focusing on the contributing factors of these alterations.

Goal(s): The objective is to clarify the relationship between choroid plexus (Chp) function and clinical characteristics of preeclampsia patients, as well as to establish a novel diagnostic approach of Preeclampsia based on imaging.

Approach: Prospective cohort study

Results: Our study revealed smaller CPV and higher susceptibility values of choroid plexus in preeclampsia patients.

Impact: This study introduces a novel indicator that utilizes choroid plexus volume and the QSM technique for early prediction of preeclampsia, potentially improving diagnostic accuracy and intervention strategies.

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