Abstract #3186

Design of a differential single-band presaturated ultrashort echo time (dSB-UTE) sequence for accelerated short-T2 imaging

Jason A Reich¹, Kevin D Harkins^2,3,4, Rachelle L Crescenzi^2,3,4, Erin L MacMillan^1,5, and Rebecca E Feldman^1,6

¹Department of Computer Science, Mathematics, Physics and Statistics, University of British Columbia, Kelowna, BC, Canada, ²Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, TN, United States, ³Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, TN, United States, ⁴Biomedical Engineering, Vanderbilt University, Nashville, TN, United States, ⁵UBC MRI Research Centre, Department of Radiology, University of British Columbia, Vancouver, BC, Canada, ⁶Biomedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States

Synopsis

Keywords: Pulse Sequence Design, Pulse Sequence Design

Motivation: Short-T2 imaging requires ultrashort echo time (UTE) sequences with long scan times. The PINS-UTE sequence uses simultaneous multi-slice techniques to reduce UTE scan times, but its prepulse results in short-T2 signal loss and out-of-slice signal.

Goal(s): To implement a novel differential single-band presaturated UTE (dSB-UTE) sequence to improve simultaneous multi-slice UTE imaging.

Approach: The dSB-UTE sequence uses single-band presaturation that is shifted in the slice-select direction between subsequent acquisitions. Subtracting acquisitions results in two simultaneous slices.

Results: The effects of prepulse flip angle on saturation band profiles are reported and we demonstrate the ability of the dSB-UTE sequence to acquire two simultaneous slices.

Impact: The dSB-UTE sequence is expected to reduce scan times for short-T2 imaging by a factor of 1.55-4.72 while achieving the same echo times as current UTE sequences. The dSB-UTE shows improved image quality over other simultaneous multi-slice UTE techniques.

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